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What should I tell my health care providers before I take Nexavar?

You should not use sorafenib if you are allergic to it, or if you have squamous cell lung cancer and you are being treated with carboplatin (Paraplatin) and paclitaxel (Onxol, Taxol, Abraxane).

To make sure sorafenib is safe for you, tell your doctor if you have:

• kidney or liver problems other than cancer;

• lung cancer;

• a bleeding or blood clotting disorder such as hemophilia;

• high blood pressure (hypertension), heart disease, slow heartbeats, congestive heart failure, chest pain;

• a personal or family history of Long QT syndrome;

• a history of stroke or heart attack; or

• any allergies.

Do not use sorafenib if you are pregnant. It could harm the unborn baby.

Use birth control to prevent pregnancy while you are receiving sorafenib, whether you are a man or a woman. Tell your doctor right away if a pregnancy occurs while either parent is taking this medication. Keep using birth control for at least 2 weeks after your treatment ends.

It is not known whether sorafenib passes into breast milk or if it could harm a nursing baby. You should not breast-feed while using Nexavar.

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